RNA Details
Disease Name
iga nephropathy
Tissue
kidney
RNA Symbol
mir-23b
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
CRISPR-Cas9
Target
NA
Pathway
NA
PubMed ID
Title
MicroRNA-23b-3p Deletion Induces an IgA Nephropathy-like Disease Associated with Dysregulated Mucosal IgA Synthesis
Year
2021
Function
Loss of miR-23b increases the susceptibility of the kidney to progressive fibrosis through loss of regulation of expression of gremlin 2 and IgA accumulation through downregulation of the transferrin receptor.